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View Full Version : Propranolol and Sertralin and my ongoing nightmare - HELP any advice welcome



livelifesronger
08-08-2016, 03:39 PM
A brief backstory, but i used to be an average smart individual educated to degree level and traveled the world solo.... despite some background depression (losing pleasure in leisure activities, finding it hard to watch tv etc) i've always managed to keep it at bay being occupied during my education and previous jobs with no meds necessary.

My recent job however was probably one way above my station which triggered unbearable amounts of anxiety, frequent panic attacks and a depression that saw me get signed off work twice. The position was too high powered for someone of my experience and a lot of work colleagues reinforced negative beliefs about myself, but hay ho a jobs a job and i'll persevere and the anxiety might normalise? the opposite happened and finally had to take the plunge and leave.
However moving into unemployed life helped temporaily, but all my anxieties began to bleed into everyday life and functioning, worries about the future, shattered confidence, even started getting anxiety over basic decision making that all withdrew me from my friends and family which in turn pulled me into a dark hole of depression.

The Dr first prescribed me propranolol to assist with the anxiety...40mg a day eventually boosted to 80mg, i was on this for about a month before heading back to the dr who prescribed a 2 week course of 50mg sertraline and reassured me of its safety and the need to persevere and this is where the nightmare begins.

Day 1 of sertraline, noticed wide dilated pupils, sweating, muscle twitching, irritability
Day 2 of sertraline. things went crazy, my mood shot up and straight down rapidly in quick succession, sheer disorientation, paranoia. I woke up with all my senses knocked out and a strong 'exhaust' like fume smell in my nose. i was convinced it was the smell of death and something compulsed me to leave the house and find a way to end my life. i was convinved this was the only way. discovering the last thread of rationaility i pulled myself into hospital. sitting in a room with an emergency therapist my ups and downs continued until i could only nod and answer basic questions! it felt like a dream world and that it wasnt really happening.
once on a more stable level i was taken home by relatives and trying to readjust to the home environment. it was then i realised i had not taken the propralonol for a few days which i continued, with my weaning off slowly.

Since this event i have been experiencing some very scary freightening symptoms that my new mental health dr cant really understand. I've lost all of my senses apart from my smell, ears are dull and vision is a bit blurred, no taste, i cant really 'feel' anything apart from if its hot or cold and the pressure it exerts. I now find myself locked down low in a very serious depression with compulsive irrational thoughts of suicice popping into my head. my body feels week without energy and trying to concentrate on even the simplist tasks is near impossible. I feel like a zombie of a human being, only being able to respond to people with basic replys, not being able to truely concentrate on what they are saying and being noticeably forgetful


It looks like i've had a very serious reaction to two sets of drugs, is anybody got any advice on what may have happened and how to get back to where i was? my mental health dr is playing the waiting game and just hoping things will get back to normal once the drugs are out of my system but ive not felt any better even after a week of the episode. every moment of every day is excrutiating and i dont feel the dr's are understanding the full weight of whats happening. if anyone can shed light on what happened maybe i can learn better as to how manage this for the sake of myself and the family around me! thank you so much!

gypsylee
08-08-2016, 06:28 PM
Hi and welcome..

Sorry you're feeling that way :(

I never even bothered with propranolol. Sertraline and all the SSRIs can definitely knock you around though. I need benzos to get through that initial phase of taking them. In my opinion - and I'm not a professional but I sure have had experience with meds - this combination is pretty nasty. Your natural brain chemistry is all out of whack but it will go back to normal. Frankly I think it's cruel not to give someone in your state any benzodiazepines. It's basically like detoxing cold turkey (which I've also done off morphine and benzos together, so I know how resilient the brain is).

Try seeing it as a detox and just take care of yourself. Rest, drink water etc. Try and do some deep breathing. If you have family support maybe they can help you find a different doctor if you don't start to get better in the next week or so.

Cheers,
Gypsy x

Anne1221
08-08-2016, 07:28 PM
Most people with anxiety are not given propranlol but rather a benzodiazepine, as gypsylee mentioned. The SSRI antidepressants have helped me tremendously, and although I don't like taking any type of benzo, one of them is saving my life right now because I have a lot of anxiety. Sertraline (if that is Zoloft) takes time to get into your system to fully work (3-4 weeks) and at the beginning you will have all types of side effects. How much confidence do you have that this doctor is the right one for you?

Kirk
08-09-2016, 06:44 AM
I am 59 now and have been on Propranolol 80mg LA since I was 50. I was put on it as I
sometimes had skipped beats and it has helped. My dose was upped from 60 to 80 in 2012. The only side effects I have had is fatigue
sometimes and vivid dreams, which are not bad at all. It may be in your best interest to consult with another physician to get their
opinion since the symtoms have persisted.

Nowuccas
08-09-2016, 10:08 AM
Hey livelifesronger,

Most of those side effects may be found at

https://www.drugs.com/sfx/sertraline-side-effects.html &

https://www.drugs.com/sfx/propranolol-side-effects.html

Your adverse reaction is an exemplar of why I rarely recommend SSRIs such as sertraline, or beta blockers like propranolol; see http://www.depressionforums.org/forums/topic/104007-starting-zoloft-my-first-prescription-for-depression/ &

* http://anxietyforum.net/forum/showthread.php?34986-Zoloft-has-ruined-me-(I-want-to-feel-normal-again)&p=228871#post228871

Suicidal compulsion; check out https://www.google.com.au/search?client=opera&q=sertraline%3B+suicidal+compulsion&sourceid=opera&ie=UTF-8&oe=UTF-8 such as:

Sertraline: MedlinePlus Drug Information
medlineplus.gov › Drugs, Herbs and Supplements
You may become suicidal, especially at the beginning of your treatment and any time ...

NAMI: National Alliance on Mental Illness | Sertraline (Zoloft)
www.nami.org › Learn More › Treatment › Mental Health Medications
Read about Sertraline, an antidepressant medication that is approved to treat adult ... It is also approved to treat obsessive-compulsive disorder (OCD) in adults, ... Low energy, trouble concentrating, or thoughts of death (suicidal thinking) ...


"it felt like a dream world and that it wasnt really happening" - seems like derealization; a post about it, with some therapeutic techniques to help deal with it may be found here*.

Other relevant posts:

ANXIETY or PANIC ATTACKS: http://anxietyforum.net/forum/showthread.php?34755-Panic-attacks-that-last-for-hours

HERBAL ANXIOLYTICS / ANTI-ANXIETY PRODUCTS: (passionflower, valerian, St. John's Wort, etc.) http://anxietyforum.net/forum/showthread.php?34269-5-Powerful-Tools-You-Probably-Haven-t-Tried-Yet&p=225415#post225415

NON HERBAL NATURAL (NON PHARMACEUTICAL) ANXIOLTYICS: (5-htp, etc.) http://anxietyforum.net/forum/showthread.php?34355-Help-Please!!!/page2

DEPRESSION: http://anxietyforum.net/forum/showthread.php?32707-has-this-happend-to-you&p=216510#post216510


"Vitamin D3 Cured my Anxiety, Depression, and Panic Disorder", (by another forum member) is at http://anxietyforum.net/forum/showthread.php?12695-Vitamin-D3-Cured-my-Anxiety-Depression-and-Panic-Disorder&highlight=vitamin

"The Quick Guide to Stopping Panic Attacks", at http://anxietyforum.net/forum/showthread.php?9512-The-Quick-Guide-to-Stopping-Panic-Attacks&highlight=admin


Your doctor may prescribe other SSRIs, or anxiolytics, but the decision whether to take them, or use the natural treatments, including relaxation methods, progressive muscle relaxation, meridian tapping technique / EFT, and non pharmaceutical based herbal and non herbal products is yours alone. Either way, I strongly suggest that you Google: "clinical psychologists; Cognitive Behavioural Therapy; (your location" and have at least 6 months of sessions, then begin weaning off all anxiolytic medications, if still taking them.

Information that your prescriber may well have relied upon to select sertraline/Zoloft was apparently ghost written; enter "Zoloft" in the searchbar at www.mercola.com
http://www.google.com/search?q=zoloft%3B+mercola&hl=en&gbv=2&oq=zoloft%3B+mercola&gs_l=heirloom-serp.12..0i7i30.730952.736388.0.739088.24.13.0.0.0 .0.1955.2436.4-1j8-1.2.0....0...1ac.1.34.heirloom-serp..22.2.2436.sPd8HPwEJR4

Pfizer—Zoloft. "A document was written that included 81 different articles promoting Zoloft's usefulness for everything from panic disorder to pedophilia. The only problem was, for some articles, the name of the author was still listed as 'to be determined,' even though the article was listed as already completed".

From http://articles.mercola.com/sites/articles/archive/2012/10/04/10-drug-company-settlements.aspx

2009: "Pfizer pays $2.3 billion for marketing fraud related to Bextra, Lyrica and other drugs. Charges included marketing drugs to doctors for uses for which they had not been approved and giving kickbacks to doctors and other health care professionals for prescribing their drugs. This was Pfizer's fourth settlement numbering in the multimillions in less than a decade".

From http://articles.mercola.com/sites/articles/archive/2010/11/18/drug-companies-are-ranked-in-the-top-100-corporate-criminals-of-the-1990s.aspx

"Too Big to Fail?

You may recall that I wrote about this -- in the largest health care fraud settlement in history, Pfizer was ordered to pay $2.3 billion to resolve criminal and civil allegations that the company illegally promoted uses of four of its drugs, including the painkiller Bextra. The other drugs were the antipsychotic Geodon, the antibiotic Zyvox, and the anti-epileptic Lyrica.

Only a few years earlier, Pfizer had paid $430 million for illegally promoting uses of its seizure drug, Neurontin.

Yet, these are just a few examples of all the "mistakes" Pfizer has made through the years, making it very clear why AllBusiness.com named this company No. 17 in the Top Corporate Criminals for the 1990s.

Technically speaking, companies found guilty of fraud like this are banned from dealing with Medicare and Medicaid again. But, as I've already reported, do you think that happened with Pfizer?

Nope.

Instead, in a slap-on-the-wrist move that resembled the too-big-to-fail bank bailouts, federal prosecutors allowed Pfizer to avoid being sentenced for massive fraud and deception by letting them form a sham company to take the fall.

So, in the end, Pfizer's "imaginary friend" Pharmacia & Upjohn shouldered the conviction, even though it had never sold any drugs. As CNN found, "the subsidiary is nothing more than a shell company whose only function is to plead guilty."

And Pfizer got off scot-free, except for that little $2.3 billion fine that amounted to just three months' profits."


You have already taken a risk and lost; so, are you feeling lucky, now that you know a little more about the untrustworthiness of the manufacturer, and the corruption inherent in the system?

Kirk
08-09-2016, 01:01 PM
As my wife, a long time pharmacist tells me, all medications, whether prescription, over the counter, etc., can have side effects.
It does not mean you will have the side effects. A determination needs to be made if the benefit outweighs any potential risk.

gypsylee
08-09-2016, 08:06 PM
I'm wondering what country the OP is in because I've noticed US doctors are less uptight about benzos than here (Australia). I'm not sure about the UK. Our GPs are restricted by the government in some way and they absolutely freak out about prescribing benzos because they're scared of losing their licence. Psychiatrists have more freedom (that's who told me about this). I completely understand how easy they are to get addicted to but in my experience they are actually a lot safer than many alternatives. In most cases here, if you go to a GP with anxiety they will prescribe an SSRI.. I've had success with those but when someone is in a bad way they're usually going to get worse before getting better. With severe anxiety/depression that can be life-threatening basically. I was lucky in a way that my anxiety surfaced in the early 90s and I was able to see a Psychiatrist free of charge every week. These days people don't have that luxury and I hate to think of what they're going through if they are just starting to experience anxiety/depression.

The other issue here is illicit drugs and alcohol. Methamphetampine is an epidemic here and alcohol is almost encouraged, so you can imagine people turning to those rather than dealing with doctors and the hell of starting an SSRI. I know of a guy who right this minute is in a (locked-down) psychiatric ward, full of meth addicts. The government knows all about this problem but they are so out of touch and so "corporatised" they just don't care.

Anyway, I guess what I'm trying to say is that I think there's a huge gap between how the medical profession are dealing with anxiety/depression and what's happening to people out there who are struggling (which is getting more and more common). I'd like to work in mental health/addiction but I'm put off because I know how frustrating and stressful it would be. It's something I'm really passionate about but I have to think of my own mental health as well.

Kirk
08-10-2016, 06:10 AM
Here in Baltimore, their is an epidemic of drug abuse. Baltimore is the Heroin capital of the USA.