Nowuccas
10-28-2015, 10:13 AM
From: http://www.vitamindcouncil.org/blog/study-finds-vitamin-d-improves-feelings-of-well-being-in-subjects-with-frequent-respiratory-tract-infections/
"Now, in another reanalysis, Bergman et al asked one question to all 124 subjects who completed the study: “How do you rate your overall health during the study year compared with the year before?” The questionnaire contained the predefined answers: 1 = better than before, 2 = worse than before, 3 = no change or 4 = other.
In the 72 subjects who said “better than before”, there was a very significant yearly increase in mean 25(OH)D levels (p<0.001). However, of those 72 subjects, only 43% obtained a final 25(OH)D of > 40 ng/ml. In the 32 subjects who reported feeling the same as before, final 25(OH)D was improved from baseline, but less significantly (p<0.05) and only 22% obtained a final 25(OH)D of 40 ng/ml. In the 14 patients who felt “worse” after the year, final 25(OH)D levels were no different than baseline.
However, what was interesting was the effect of vitamin D supplementation on the 22 patients taking antidepressants. Ten of the subjects on antidepressants felt “better”, and four of them could terminate their antidepressant use. In the figure below, of those four (red lines), three had final 25(OH)D levels > 40 ng/ml (100 nmol/L)."
Dr. John Cannell, of the vitaminDcouncil.org comments:
"Due to the very small sample size, these findings remain inconclusive. However, in my practice of psychiatry, I have seen some uncomplicated mild to moderate clinical depression improve with 5,000 to 10,000 IU/day of vitamin D. I have never seen vitamin D help treatment resistant major depression, which are the cases with severe symptoms that have not improved on multiple antidepressants."
__________________________________________________ __________________________________________________ ___________________________
Some info on VITAMIN D:
The govt. RDI of 400 IU daily is long outdated, and based on misinformation, according to Dr. John Cannell, at the VitaminDcouncil. Dr. Weil, Dr. Ben Kim, Dr. Axe, Dr. Gominak, a neurologist, and Dr. Mercola* all agree that an RDI of 5000 IU daily is not excessive, although higher levels may be required as people age, and / or put on weight. My doctor, on the basis of several peer reviewed studies, also agrees that an RDI of 5000 IU daily is not excessive, and it is virtually impossible to get the required amount from dietary sources, without the risk of toxicity.
* VITAMIN D DOSE RECOMMENDATIONS
AGE DOSAGE
"Below 5: 35 units per pound per day
Age 5 - 10: 2500 units
Adults: 5000 units
Pregnant Women: 5000 units
WARNING:
There is no way to know if the above recommendations are correct. The ONLY way to know is to test your blood. You might need 4-5 times the amount recommended above. Ideally your blood level of 25 OH D should be 60ng/ml".
The NOAEL (No observed adverse effect level) specified by the Institute of Medicine is 10,000 IU/day. Around 1 person in 300 is allergic to it, so start out with only 1,000 IU on the first day, if supplementing.
Dr. Gominak now recommends optimising vitamin D levels in the range 60 ng/ml to 80 ng/ml, and Dr. Mercola recommended 60 ng/ml or 150 nmol/litre, which is now my target level.
Vitamin D is not a true vitamin, but a hormonal substrate that is vitally important for the activation of almost 3,000 genes in the body. Its main cofactors are: zinc, magnesium, vitamin K2, and boron.
Google: "How To Make Sure That You Are Getting Enough Vitamin D; Dr. Ben Kim", then: "My 1 hr free lecture on vitamin D; Dr. Mercola".
Note that most doctors would regard as acceptable lower levels of vitamin D than those recommended by Dr. John Cannell of the vitamin D council, or Professor Michael Holick, a former member, and an expert in vitamin D.
Read: "Why are doctors reluctant to accept vitamin D", at:
http://www.vitamindwiki.com/Why+are+doctors+reluctant+to+accept+vitamin+D and in particular:
"Would you be opposed to my getting more vitamin D", at:
http://www.vitamindwiki.com/tiki-index.php?page_id=3162
Also view http://www.vitamindcouncil.org/about-vitamin-d/how-do-i-get-the-vitamin-d-my-body-needs/ & www.sawyer.com/understanding-uva-uvb/ & http://articles.mercola.com/sites/articles/archive/2014/10/19/cholesterol-sulfate.aspx Consider the UV meter shown in vitaminDcouncil.org at Sunfriend.com
"Now, in another reanalysis, Bergman et al asked one question to all 124 subjects who completed the study: “How do you rate your overall health during the study year compared with the year before?” The questionnaire contained the predefined answers: 1 = better than before, 2 = worse than before, 3 = no change or 4 = other.
In the 72 subjects who said “better than before”, there was a very significant yearly increase in mean 25(OH)D levels (p<0.001). However, of those 72 subjects, only 43% obtained a final 25(OH)D of > 40 ng/ml. In the 32 subjects who reported feeling the same as before, final 25(OH)D was improved from baseline, but less significantly (p<0.05) and only 22% obtained a final 25(OH)D of 40 ng/ml. In the 14 patients who felt “worse” after the year, final 25(OH)D levels were no different than baseline.
However, what was interesting was the effect of vitamin D supplementation on the 22 patients taking antidepressants. Ten of the subjects on antidepressants felt “better”, and four of them could terminate their antidepressant use. In the figure below, of those four (red lines), three had final 25(OH)D levels > 40 ng/ml (100 nmol/L)."
Dr. John Cannell, of the vitaminDcouncil.org comments:
"Due to the very small sample size, these findings remain inconclusive. However, in my practice of psychiatry, I have seen some uncomplicated mild to moderate clinical depression improve with 5,000 to 10,000 IU/day of vitamin D. I have never seen vitamin D help treatment resistant major depression, which are the cases with severe symptoms that have not improved on multiple antidepressants."
__________________________________________________ __________________________________________________ ___________________________
Some info on VITAMIN D:
The govt. RDI of 400 IU daily is long outdated, and based on misinformation, according to Dr. John Cannell, at the VitaminDcouncil. Dr. Weil, Dr. Ben Kim, Dr. Axe, Dr. Gominak, a neurologist, and Dr. Mercola* all agree that an RDI of 5000 IU daily is not excessive, although higher levels may be required as people age, and / or put on weight. My doctor, on the basis of several peer reviewed studies, also agrees that an RDI of 5000 IU daily is not excessive, and it is virtually impossible to get the required amount from dietary sources, without the risk of toxicity.
* VITAMIN D DOSE RECOMMENDATIONS
AGE DOSAGE
"Below 5: 35 units per pound per day
Age 5 - 10: 2500 units
Adults: 5000 units
Pregnant Women: 5000 units
WARNING:
There is no way to know if the above recommendations are correct. The ONLY way to know is to test your blood. You might need 4-5 times the amount recommended above. Ideally your blood level of 25 OH D should be 60ng/ml".
The NOAEL (No observed adverse effect level) specified by the Institute of Medicine is 10,000 IU/day. Around 1 person in 300 is allergic to it, so start out with only 1,000 IU on the first day, if supplementing.
Dr. Gominak now recommends optimising vitamin D levels in the range 60 ng/ml to 80 ng/ml, and Dr. Mercola recommended 60 ng/ml or 150 nmol/litre, which is now my target level.
Vitamin D is not a true vitamin, but a hormonal substrate that is vitally important for the activation of almost 3,000 genes in the body. Its main cofactors are: zinc, magnesium, vitamin K2, and boron.
Google: "How To Make Sure That You Are Getting Enough Vitamin D; Dr. Ben Kim", then: "My 1 hr free lecture on vitamin D; Dr. Mercola".
Note that most doctors would regard as acceptable lower levels of vitamin D than those recommended by Dr. John Cannell of the vitamin D council, or Professor Michael Holick, a former member, and an expert in vitamin D.
Read: "Why are doctors reluctant to accept vitamin D", at:
http://www.vitamindwiki.com/Why+are+doctors+reluctant+to+accept+vitamin+D and in particular:
"Would you be opposed to my getting more vitamin D", at:
http://www.vitamindwiki.com/tiki-index.php?page_id=3162
Also view http://www.vitamindcouncil.org/about-vitamin-d/how-do-i-get-the-vitamin-d-my-body-needs/ & www.sawyer.com/understanding-uva-uvb/ & http://articles.mercola.com/sites/articles/archive/2014/10/19/cholesterol-sulfate.aspx Consider the UV meter shown in vitaminDcouncil.org at Sunfriend.com