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Turd_Ferguson
09-09-2014, 11:51 AM
Get ready for a rambling post ramblers:

I've suffered from life long anxiety and very mild OCD. The OCD is practically gone but the anxiety and a case of insomnia have really kicked in the last 5 years or so.

It was within that 5 years that I first began taking medication (prescribed of course) to treat the condition. Studying pharmacology and observing what doctors tend to do base on friends, I know they mostly have their preferred drugs (SSRIs, SNRIs, atypicals, and eventually TCAs) and they just go down the list until the find one that works (of course benzos as well but some are more willing than others to prescribe them). Then if that doesn't work they label you bipolar and start down another list. I KNOW I am not bipolar. I have never had a manic episode in my life. Any serotonin reuptake inhibitor seems to make me shaky as hell once it reaches a certain blood concentration and makes my anxiety 10x worse.

*Fun fact, all the 5HT2a antagonists would do the exact opposite of make me drowsy. A new doctor I had tried to prescribe me it for sleep and I chuckled for a bit. Nefazodone helped a bit but the sensation of my skin being on fire all day was slightly unpleasant.


The ironic thing is even though I am anxious often, in most situations I am cool calm, and down to Earth. I don't delusions of grandeur. The only thing that has really helped me is clonazepam or alprozolam for the rare panic attack. The clonazepam helps me get to sleep by stopping my thoughts from racing.

As a last ditch, one of my docs prescribed adderall which made me hyper as hell and the crash was awful. Then I asked him about dexmethylphenidate and we gave that a try. It was wondrous for about 4 months. It was everything I wanted. My anxiety was gone, I felt better about getting work done, and I was more outgoing like I used to be. It was like my old self circa 2009. But then some life events turned everything to shit and I found myself getting depressed once it wore off. Clonazepam seemed to make the depression worse at times. Now I've been on Vilazodone which is making things WORSE so I have stopped it. Its somehow shifted my sleep wake cycle to roughly 5 hours from 11pm to 4am. Taking 3x the dose of my clonazepam was the only thing that could get me back to sleep. When I don't sleep things are much worse the next day. I wake up every morning depressed and anxious at this point and am freezing cold in rooms that are 75F. I just stopped the Vilazodone today after tapering up to 20mg and then back down to 10.

My question is does has anyone had a similar experience and ever found anything that actually helps them?

List of drugs prescribed in the past: Fluoxetine (Prozac), Lexapro, Cymbalta, Effexor (nightmare), Viibryd (Vilazodone), Nortriptyline, Trazodone, Nefazodone, Adderall, Dexmethylphenidate, alprozolam, and clonazepam.

Supplements I've tried: Dozens! But I found "Phenibut" Phenyl-amino-butyric acid to actually work (it actually a prescription drug in Russia). It just suffers from the same issues with dependence that benzos do.

Dahila
09-09-2014, 12:17 PM
Hi welcome to the forum. I tried most of them and I can not take any SSRI medication, finally the mix of gabapentin and clonazepam, just small dose 0.5 on evening, when my anxiety hits... lately I cut down on Zoplicone, I take half of that before sleep. My anxiety is gone or maybe not gone but I am calm. Life is good now. I had my last panic attack 5 months ago when my close friend passed away. Everyone would get one or two i this situation. I use ativan then. it took at least a half of year before she found the combination which works for me. No supplements helps me, not the ones available here. Back home i was using for years hand picked herbs. Try the lemon balm,hops, valerian. lavender, St. John wort; this can not be used with AD. Mulungu, ginseng, camolile, albizia they are helpful but they do not help me enough. I make Melisa extract and take a shot from time to time, it seems to help a bit:)
People claim that D3, magnesium cure their anxiety, I believe it is helpful but no cure ;))

Anne1221
09-09-2014, 02:33 PM
Lexapro works great for me. I like it better than Prozac, Paxil and Effexor that I tried. The only one you haven't tried is Wellbutrin, but I think it helps more with depression than anxiety, although some say it helps their anxiety.

Turd_Ferguson
09-10-2014, 06:01 AM
Thank you for the reply. I have tried Magnesium which gave me horrible gas. Valerian root definitely seemed to work a bit.

Dahila
09-10-2014, 09:18 AM
Turd just make a break with valerian I do not remember exactly but it not suppose to be taken every day, or after 7 days make a break of 14 this is the golden rule with herbs;)) good luck

Turd_Ferguson
09-10-2014, 11:08 AM
Turd just make a break with valerian I do not remember exactly but it not suppose to be taken every day, or after 7 days make a break of 14 this is the golden rule with herbs;)) good luck

Yes, thanks for the advice, I have heard of possible liver issues with valerianic acid in valerian root with extended use similar to what I've heard regarding Kava Kava. For now I'm going to drop any sort of stimulant and stick with benzos and or phenibut for a bit. It has worked in the past and I'll see how the next week or so goes. Phenibut really is a fascinating compound though. It helps clear the mind and allows you to fall asleep without feeling very sedated.

Dahila
09-10-2014, 11:25 AM
Phnibut was it studied on people? I thought is is not approved yet. I know it is supplement, but can not find any interaction with other meds :) glad something helps you. The only herb you can use regularly is camomile and lemon balm aka melissa, even with it, you need to take breaks :)

Turd_Ferguson
09-11-2014, 06:42 AM
Phnibut was it studied on people? I thought is is not approved yet. I know it is supplement, but can not find any interaction with other meds :) glad something helps you. The only herb you can use regularly is camomile and lemon balm aka melissa, even with it, you need to take breaks :)

Phenibut is prescribed mainly in Russian and former Soviet block countries. It was given to cosmonauts on missions because it kept them calm with out sedating them. In my experience it does slightly enhance the sedative effects of some medicines but only in high doses. Definitely NOT to be take with alcohol as with any similar drug.

Dahila
09-11-2014, 09:48 AM
I was wondering about it, of course it is not available here I think. You know Russia has a lot of good stuff, in such huge country. People there know more about herbs that anywhere else. :)

Turd_Ferguson
09-11-2014, 09:57 AM
I was wondering about it, of course it is not available here I think. You know Russia has a lot of good stuff, in such huge country. People there know more about herbs that anywhere else. :)

Its actually very available here. Its sold as a nutritional or work out supplement because it is an amino acid derivative and somehow falls under the FDA's rules to be sold as such. Its available on eBay and quite a few other websites.