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justme55
01-30-2014, 01:13 PM
Question anyone that can help. Can changing manufactures make a difference in meds. I was taking mirtazapine by a certain company and they switched it up on me giving me mirtazapine from a different company. Didn't think anything of it at the time but could this be causing my health issues. Asked the psych, he said "maybe so." Would like to hear from you guys.

Thanks for your input!
Going to call the pharmacy to ask.

jessed03
01-30-2014, 02:28 PM
Hm James, seems as if you're speaking my language tonight. Mirtazapine and wheat allergies. Two of my past times :)

I was given lots of different branded Mirtazapine, and I found different side effects with each brand a lot of the time. Some would make me hungrier, some would give me restless legs. I knew by my symptoms after taking it .

It pretty much stayed at the same level therapy wise though. I don't remember any specific brand being weaker, or less potent than another. They all seemed to be pretty level despite the weird side effects certain brands gave me.

My research in this: Most will deny it, and say a difference doesn't exist, and tbh, nobody bothers to fund any research, so no one truly knows. The drug companies don't bother as they're worried the product will prove as effective, therefore their original product will seem too expensive compared to the copy, and the ones who make the copy don't wanna fund it, incase theirs comes out inferior. So there's a stalemate!

So yeah, I definitely felt issues side effect wise when switching brands, but not mood wise.

The best thing to do is find one brand you like, and stick with it if you can! Even if it means going to a different pharmacy or asking for them to switch your brand.

Let me know what happens for you here! :)

alankay
01-31-2014, 03:53 PM
There can be some variation with the way the med works it way into your system. It's not supposed to be different in any significant way but sometimes a person will feel a difference.
For example I prefer valium from Watson. Seems abit better for me than valium(diazepam) from mylan or teva but that's just me. Alankay

nicnic73
02-14-2014, 08:18 PM
My Doc informed me that generic drugs only have to be 80% effective to be considered safe from the FDA as a replacement for name brand. Pharm Companies can use different formulas for the other 20%. I for one have tried two different generics for Lexapro and within weeks felt horrible. So I am left with no choice other than to pay $180 per mth for name brand and that's with my insurance. Thank you FDA!

jessed03
02-14-2014, 08:34 PM
My Doc informed me that generic drugs only have to be 80% effective to be considered safe from the FDA as a replacement for name brand. Pharm Companies can use different formulas for the other 20%. I for one have tried two different generics for Lexapro and within weeks felt horrible. So I am left with no choice other than to pay $180 per mth for name brand and that's with my insurance. Thank you FDA!

That sucks. Lexapros meant to be one of the worst for generic versions.